2-(3-bromo-4-fluorophenyl)-2,2-difluoroacetic acid - Names and Identifiers
2-(3-bromo-4-fluorophenyl)-2,2-difluoroacetic acid - Introduction
2-(3-bromo-4-fluorophenyl)-2,2-difluoroacetic acid is an organic compound with the chemical formula C8H4BrF2O2.
Its properties are as follows:
-Appearance: White crystalline solid
-Melting point: about 70 ° C
-Boiling point: About 254 ° C
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol and ether
2-(3-bromo-4-fluorophenyl)-2,2-difluoroacetic acid can be used as a reaction reagent in organic synthesis, especially in the preparation of drugs and pesticides.
Its preparation method can generally be carried out through the following steps:
1. Under low temperature conditions, 3-bromo-4-fluorobenzyl alcohol is reacted with oxidant to obtain 3-bromo-4-fluorobenzaldehyde.
2. 3-bromo-4-fluorobenzaldehyde reacts with difluoroacetic acid to generate 2-(3-bromo-4-fluorophenyl)-2,2-difluoroacetic acid.
When using and handling 2-(3-bromo-4-fluorophenyl)-2,2-difluoroacetic acid, you need to pay attention to the following safety information:
-Avoid direct contact with skin and eyes. If there is contact, rinse immediately with plenty of water.
-Avoid inhaling the dust or vapor of this compound during operation, as it may be harmful to health.
-During storage and use, it should be placed in a sealed container, away from fire and high temperature environment.
-When handling the compound, follow laboratory safety procedures and use appropriate personal protective equipment, such as laboratory gloves and protective glasses.
Last Update：2024-04-09 19:05:55